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Cytarabin ist ein Isomer des Nukleosids Cytidin. Es besteht aus einer Furanose und dem Cytosin. Es enthält – im Gegensatz zu den meisten Nukleosiden – anstelle der β-D-Ribofuranose die β-D-Arabinofuranose und gehört damit zur Gruppe der. Araç ist eine Stadt und Hauptort des gleichnamigen Landkreises in der in Provinz Kastamonu in der zentralen Schwarzmeerregion (türkisch Orta Karadeniz. Der Arac ist ein Fluss in Frankreich, der im Département Ariège in der Region Okzitanien verläuft. Er entspringt anfangs unter dem Namen Ruisseau des. Cytarabin (ARAC, ARA-C). Der folgende Text informiert über Anwendung, Wirkung und mögliche Nebenwirkungen des Cytarabins sowie darüber, welche. 8 Übersetzungen für das Wort araç vom Türkischen ins Deutsche. Übersetzung Französisch-Deutsch für arac im PONS Online-Wörterbuch nachschlagen! Gratis Vokabeltrainer, Verbtabellen, Aussprachefunktion. Übersetzung für 'araç' im kostenlosen Türkisch-Deutsch Wörterbuch und viele weitere Deutsch-Übersetzungen.

Arac How Cytarabine Is Given: Video
GODMODE - Afterbirth's #1 Mod [Arac]Its mode of action is due to its rapid conversion into cytosine arabinoside triphosphate , which damages DNA when the cell cycle holds in the S phase synthesis of DNA.
Rapidly dividing cells, which require DNA replication for mitosis , are therefore most affected. Cytarabine is the first of a series of cancer drugs that altered the sugar component of nucleosides.
Other cancer drugs modify the base. Cytarabine is often given by continuous intravenous infusion, which follows a biphasic elimination — initial fast clearance rate followed by a slower rate of the analog.
Several mechanisms of resistance have been reported. However, cytarabine treatment was only effective for herpesvirus infection in a murine model.
It is also known as ara-C arabinofuranosyl cytidine. From Wikipedia, the free encyclopedia. Chemical compound chemotherapy medication. For a person, see Georg Friedrich Alexan.
IUPAC name. Interactive image. Archived from the original on 11 June Retrieved 8 December British Medical Association. Robin Analogue-based Drug Discovery.
Archived from the original on World Health Organization model list of essential medicines: 21st list Geneva: World Health Organization. October Nov Antimicrob Agents Chemother.
December Expert Opinion on Drug Delivery. The Chemotherapy source book. Semin Oncol. Cancer Treat Res. Cancer Treatment and Research.
Chem Rev. Biochem Pharmacol. Bibcode : PLoSO.. Nat Med. Unfortunately, chemotherapy does not know the difference between the cancerous cells and the normal cells.
The "normal" cells will grow back and be healthy but in the meantime, side effects occur. Different drugs may affect different parts of the body.
Cytarabine belongs to the category of chemotherapy called antimetabolites. Antimetabolites are very similar to normal substances within the cell.
When the cells incorporate these substances into the cellular metabolism, they are unable to divide. Antimetabolites are cell-cycle specific.
They attack cells at very specific phases in the cycle. Note: We strongly encourage you to talk with your health care professional about your specific medical condition and treatments.
The information contained in this website is meant to be helpful and educational, but is not a substitute for medical advice. For information about the 4th Angel Mentoring Program visit www.
Toggle navigation. Spanish About Chemocare. It is also used to treat Hodgkin's lymphoma, as well as meningeal leukemia and other types of lymphoma cancers found in the lining of the brain and spinal cord.
Another method it is given is by intrathecal infusion. This method is used when drugs need to reach the cerebrospinal fluid CSF the fluid that is surrounding the brain and spinal cord, the drug is infused directly into the spinal fluid.
There is no pill form of cytarabine. Side Effects: Important things to remember about the side effects of cytarabine: Most people do not experience all of the cytarabine side effects listed.
Cytarabine side effects are often predictable in terms of their onset, duration, and severity. Cytarabine side effects will improve after therapy is complete.
Cytarabine side effects may be quite manageable. There are many options to help minimize or prevent the side effects of cytarabine. Your white and red blood cells and platelets may temporarily decrease.
Nadir: White blood cells: days, platelets: days. Nausea and vomiting Mouth sores usually occur days after therapy.
Increases in blood tests measuring liver function. These return to normal once treatment is discontinued. More often associated with high-dose regimens.
Pain, redness and skin peeling of the palms of hands and soles of feet hand-foot syndrome may occur with high-dose therapy rare. Use of steroid creams or moisturizers may be helpful.
Blood test abnormalities: Increase in blood level of uric acid. A medication called allopurinal may be given to decrease these levels.
Temporary hair loss uncommon, but thinning may occur. Eye pain , tearing, sensitivity to light and blurred vision may occur with high-dose therapy.
Often steroid drops or ointment to the eyes are used to prevent or relieve this condition. Onset is usually 5 days after treatment and may last up to 1 week.
More often these toxicities are mild and reversible. When To Contact Your Doctor or Health Care Provider: Contact your health care provider immediately, day or night, if you should experience any of the following symptoms: Fever of Chest pain or heart palpitations Inability to pass urine The following symptoms require medical attention, but are not an emergency.
Contact your health care provider within 24 hours of noticing any of the following: Diarrhea episodes in a 24 hour period Nausea unable to drink fluids and unrelieved with prescription medication.
Precautions: Before starting cytarabine treatment, make sure you tell your doctor about any other medications you are taking including prescription, over-the-counter, vitamins, herbal remedies, etc.
Do not take aspirin, products containing aspirin unless your doctor specifically permits this. Do not receive any kind of immunization or vaccination without your doctor's approval while taking cytarabine.
Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category D cytarabine may be hazardous to the fetus.
Women who are pregnant or become pregnant must be advised of the potential hazard to the fetus.
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